What is an Ostarine and Cardarine Stack?

If you’re a weightlifter, you may have heard of the term “stack.” This word is often used in the bodybuilding community to describe the use of two or more supplements together.

In this blog post, we will discuss what an Ostarine and Cardarine stack is, how it works, and whether or not it’s safe to use. We’ll also provide some tips on how to create your own stack safely and effectively.

What Is Ostarine?

Also known as the MK-2866, Ostarine was first developed by GTx Inc in an attempt to transform the compound into a potential SARM.

You’ll also hear Ostarine called EnoboSARM and there aren’t many studies that have been done to show its effectiveness.

What we do know is it’s a selective androgen receptor modulator (SARM) that was developed to treat muscle wasting diseases and certain types of cancer.

It has been known to stimulate the growth of lean mass and the company that created it has has preliminary trials done.

What Is Cardarine?

Cardarine is also called GW-501516 and GlaxoSmithKline manufactured the SARM.

It was developed as a treatment for cholesterol and obesity and other health-related conditions like diabetes, metabolic syndrome, and muscle wasting.

Cardarine is unique because it’s more of a PPAR agonist, which means it binds to the peroxisome proliferator-activated receptor delta (PPAR-delta).

This helps increase the body’s sensitivity to insulin, burn fat, and build muscle.

How Do They Work?

Ostarine works by binding to the androgen receptors in your muscles, which results in anabolic activity.

This helps you build lean mass by increasing protein synthesis and nitrogen retention.

Cardarine, on the other hand, helps increase endurance and stamina by improving fat metabolism.

It does this by activating AMPK, which is an enzyme that helps regulate metabolism.

Cardarine also helps increase glucose uptake in your muscles, which provides them with more energy.

Why Do Bodybuilders Use Cardarine and Ostarine Stacks?

Long-term use of SARMs is shown to boost your metabolism and also your protein synthesis.

When your body produces more protein synthesis it means that you can gain more muscle mass and lose more fat. And when your metabolism is higher, you’re able to burn more fat for energy.

The two SARMs are often stacked together because they complement each other well. While Ostarine helps you build muscle, Cardarine helps you burn fat. So, by using both SARMs, you can achieve a more shredded and defined physique.

You might also receive more support in building stronger joints, bones, immune systems, and muscle injuries.

The Dosages and Cycle Length of Cardarine and Ostarine

It is usually recommended to take a Cardarine and Ostarine stack up to eight weeks long. You should be taking both once a day for the entirety of the eight weeks.

You’ll want to take slightly more Ostarine than you do Cardarine. About 15mg of Ostarine should be enough while 10mg of Cardarine is all you will need.

It should be noted that taking more of each compound is not going to lead to faster or better results.

If anything, you might experience worse side effects from over-taking doses of Cardarine and Ostarine.

Results You Can Expect

The results of this stack are mostly anecdotal since there have been no official studies done but they are promising nevertheless.

You can expect to lose anywhere from 8%-10% in body fat by using the two in eight weeks. This might seem unlikely but there have been many accounts of its effectiveness.

You would think that with the big loss in weight a loss of muscles would also be a result, but most weightlifters who have seen this amount of weight loss have been able to sustain up to 95% of their muscle.

Potential Side Effects of Stacking

Even though the results are promising that doesn’t mean that stacking Cardarine and Ostarine doesn’t have its potential side effects.

The most common one is suppression which can be anything from a decrease in natural testosterone production to a complete shutdown. This is especially true if you go above the recommended dosage amounts listed above.

Headaches are another potential side effect and are a cause of the Ostarine. It can usually appear at the start of a cycle but should disappear within the first week.

Cardarine and Ostarine are known as what is called hepatoxic. This means that over time it can damage your liver because it elevates your liver enzymes.

But, this is only if you’re taking large dosages for an extended period of time. If you stick to the recommended dosage and cycle length then you shouldn’t have any problems with liver damage.

You can take milk thistle or TUDCA in order to counteract the damage done to your liver while taking this stack together.

Other potential side effects include hair loss, acne, and an increase in cholesterol levels. These are all mostly dose-dependent though and will only occur if you’re taking too much of either compound.


What is the most powerful SARM stack?

Cardarine Ostarine stack are known as the most powerful SARMs to take together. The evidence is primarily anecdotal since there have not been any human studies done.

Is Ostarine for bulking and cutting?

Ostarine is great for both bulking and cutting because it helps you build muscle burn fat, and build strength.

Does Ostarine suppress testosterone?

If taken at high doses over a long period of time there is some anecdotal evidence that suggests testosterone may be lowered.

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Jason Hughes
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