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3 Top Nitric Oxide Supplements for Men

Jason Hughes
Published by Jason Hughes
Fact checked by Markus Oliver, BHSc FACT CHECKED
Last updated: June 16, 2022

It can be a difficult journey to choose the stack of supplements that are right for your health and fitness routine. While most companies market to you what they think you should have, it is important to be knowledgeable about the quality of supplements that you may need for your body. Whether this means talking to a healthcare professional about what you are lacking, or studying it by yourself, we aim to provide the best information in each article for your goals. Nitric oxide occurs in the body, so it is extremely beneficial as a supplement, and if you are healthy, there are not many side effects that are of concern.

In this article, we will review what nitric oxide is, and what the purported benefits are. Finally, we'll talk about the top three best nitric oxide supplements that you can find on the market, as well as review foods that are naturally high in this precious molecule.

Nitric oxide occurs in the body, so it is extremely beneficial as a supplement, and if you are healthy, there are not many side effects that are of concern.

What is Nitric Oxide?

As previously mentioned, nitric oxide is a molecule that is produced naturally in the body. They are usually as a result of food ingestion or through the production of amino acids such as L-arginine and L-cirtrulline. Foods that are high in this amino acid include meats, dairy, poultry and fish. There are also some vegan foods that contain this, (mainly L-citrulline), such as legumes, nuts and even watermelon. Nitric oxide is often sold as a supplement, especially if you are a vegetarian or vegan, as your body may not be creating enough.

The function of nitric oxide is vasodilation, which means it expands or even relaxes the muscles within blood vessels and arteries, usually decreasing blood pressure by allowing more blood to flow throughout your body. This is not always a good thing, as low blood pressure may not arrive to all parts of your body, especially when consumed with other vasodilators such as alcohol.

Nitric oxide is primarily made for the bodybuilding community to increase their pump; however certain medications and supplements can be prescribed to patients that are lacking in nitric oxide, such as those suffering from erectile dysfunction, diabetes, and associated heart disease issues.

What are the Benefits of Nitric Oxide?

There are four main benefits that have been observed with a healthy amount of nitric oxide in the body, as well as some other benefits that are less commonly known:

  1. Reduces risk of heart disease: Nitric oxide reduces the stiffness in your arteries as a vasodilator, which either reduces blood pressure or helps to clean some of the plaque on the arterial walls that may have come with a high-cholesterol diet, diabetes or obesity in general. The increased blood flow may help those that are suffering from things such as varicose veins or pain, as the additional blood can restore feeling within that area.
  2. Growth and Recovery: Because of the added affects of nitric oxide on the cardiovascular and circulatory system of the body, it is theorized that these supplements can enhance muscle growth by delivering extra oxygen to the muscles themselves and throughout the body. This can help in the synthesis of protein and also speed up the recovery time between sets or workouts so that you can get back to the gym quicker.
  3. It may alleviate physical problems with impotence: Erectile dysfunction can be caused in three different ways: psychological (mental), shocks or diminished libido, and finally, physical problems associated with blood flow to the reproductive organ or the muscles therein. Doctors may prescribe extra nitric oxide containing foods or supplements to your diet in order to increase blood flow if you have this issue. The increased blood flow may serve to alleviate some of the issues with impotence.
  4. Improves lung function:  Not only does nitric oxide help those with blood flow issues or heart problems, but it also increases the amount of oxygen intake throughout the body. This can help with certain issues that prevent you from getting enough air into your lungs, such as cystic fibrosis.

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  • L-Arginine and Performance enhancement:
  • L-Arginine has been researched to a very limited extend however, evidence supports a possible exercise enhancement as L-arginine may increase nitric oxide in the body, which could potentially improve blood flow and oxygen to muscle tissue. For example, a 2017 randomized study in 56 male soccer players found that treatment with 2 grams of L-arginine daily for 45 days significantly increased sport performance, compared with a placebo group.
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    The Best Nitric Oxide Supplements

    Huge Supplement Advanced Nitric Oxide Formula

    This supplement contains L-Arginine and beet root extract, both useful in the creation of nitric oxide within the body. L-arginine is usually lacking from a vegan diet.

    Pros: Generous pump for your workout, increased muscle endurance, increased vascularity

    Cons: This supplement focuses mostly on a pump, so this may not be a great supplement for those with health conditions.

    ONNIT Total Nitric Oxide

    Contains both L-Arginine, L-Citrulline, beet root and tart cherry. All are ingredients that increase the production of nitric oxide within the body.

    Pros: Increases cellular integrity, focuses on heart health, massive increase in vascularity and vasodilation during exercise

    Cons: The product focuses on health and fitness, so this product is right for everyone - however advanced bodybuilders may find this works too slow.

    N.O. XT Nitric Oxide Booster

    Finally, the N.O XT Nitric Oxide Booster Contains L-Citrulline, L-Gluthathone, Nitrosigine, and BioPerine, does not contain L-Arginine. The supplement will work differently than others as it focuses more on antioxidant production than nitric oxide, but both are extremely useful for workouts.

    Pros: Less muscle fatigue, better immune system, protection from free radicals, more power output overall

    Cons: Lack of L-Arginine may not deliver the full pump necessary for an advanced workout


    What is the best nitric oxide supplement?

    We have listed three of the best oxide supplements on the market. If you are still not satisfied with that selection, here is an article we wrote on the best 11 nitric oxide supplements.

    Where is nitric oxide produced in the body?

    Nitric oxide is produced in the inner lining of the blood vessels by our endothelial cells. They help with the synthesis of oxygen and nitrogen throughout the body.

    Can nitric oxide help migraines?

    Migraines that are caused by lack of blood flow to the brain can be alleviated with additional nitric oxide, as it helps to increase blood flow throughout the body due to its relaxing of the arterial walls.

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